Combination Therapy with Terbinafine and Amphotericin B in a Rabbit Model of Experimental Invasive Aspergillosis

Antagonistic effects of combination therapy using amphotericin B (AmB) with agents which block ergosterol synthesis are a concern. Terbinafine was evaluated with AmB to assess antagonism or synergy in a rabbit model of invasive aspergillosis. Terbinafine had relatively little activity but did not de...

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Detalhes bibliográficos
Main Authors: Kirkpatrick, William R., Vallor, Ana C., McAtee, Robert K., Ryder, Neil S., Fothergill, Annette W., Rinaldi, Michael G., Patterson, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280177/
https://ncbi.nlm.nih.gov/pubmed/16251321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4751-4753.2005
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