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A Class of Pantothenic Acid Analogs Inhibits Plasmodium falciparum Pantothenate Kinase and Represses the Proliferation of Malaria Parasites

The growth and proliferation of the human malaria parasite Plasmodium falciparum are dependent on the parasite's ability to obtain essential nutrients. One nutrient for which the parasite has an absolute requirement is the water-soluble vitamin pantothenic acid (vitamin B(5)). In this study, a...

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Detalles Bibliográficos
Main Authors: Spry, Christina, Chai, Christina L. L., Kirk, Kiaran, Saliba, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280137/
https://ncbi.nlm.nih.gov/pubmed/16251308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4649-4657.2005
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