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Targeting the Shikimate Pathway in the Malaria Parasite Plasmodium falciparum

The shikimate pathway presents an attractive target for malaria chemotherapy. Three shikimic acid analogs exhibited different effects on Plasmodium falciparum growth. (6R)-6-Fluoro-shikimate and (6S)-6-fluoro-shikimate inhibited growth (50% inhibitory concentrations, 1.5 × 10(−5) and 2.7 × 10(−4) M,...

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Bibliografske podrobnosti
Glavni avtor: McConkey, Glenn A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89043/
https://ncbi.nlm.nih.gov/pubmed/9869588
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