Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for Resistance

GW678248, a novel nonnucleoside reverse transcriptase inhibitor, has been evaluated for anti-human immunodeficiency virus activity in a variety of in vitro assays against laboratory strains and clinical isolates. When GW678248 was tested in combination with approved drugs in the nucleoside and nucle...

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Detalles Bibliográficos
Autores principales: Hazen, Richard J., Harvey, Robert J., St. Clair, Marty H., Ferris, Robert G., Freeman, George A., Tidwell, Jeffrey H., Schaller, Lee T., Cowan, Jill R., Short, Steven A., Romines, Karen R., Chan, Joseph H., Boone, Lawrence R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280120/
https://ncbi.nlm.nih.gov/pubmed/16251284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4465-4473.2005
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