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Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for Resistance

GW678248, a novel nonnucleoside reverse transcriptase inhibitor, has been evaluated for anti-human immunodeficiency virus activity in a variety of in vitro assays against laboratory strains and clinical isolates. When GW678248 was tested in combination with approved drugs in the nucleoside and nucle...

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Bibliografiske detaljer
Main Authors: Hazen, Richard J., Harvey, Robert J., St. Clair, Marty H., Ferris, Robert G., Freeman, George A., Tidwell, Jeffrey H., Schaller, Lee T., Cowan, Jill R., Short, Steven A., Romines, Karen R., Chan, Joseph H., Boone, Lawrence R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280120/
https://ncbi.nlm.nih.gov/pubmed/16251284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4465-4473.2005
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