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Antiviral Activity of GW678248, a Novel Benzophenone Nonnucleoside Reverse Transcriptase Inhibitor

The compound GW678248 is a novel benzophenone nonnucleoside reverse transcriptase inhibitor (NNRTI). Preclinical assessment of GW678248 indicates that this compound potently inhibits wild-type (WT) and mutant human immunodeficiency virus type 1 (HIV-1) reverse transcriptase in biochemical assays, wi...

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Bibliografiske detaljer
Main Authors: Ferris, Robert G., Hazen, Richard J., Roberts, Grace B., St. Clair, Marty H., Chan, Joseph H., Romines, Karen R., Freeman, George A., Tidwell, Jeffrey H., Schaller, Lee T., Cowan, Jill R., Short, Steven A., Weaver, Kurt L., Selleseth, Dean W., Moniri, Kelly R., Boone, Lawrence R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251513/
https://ncbi.nlm.nih.gov/pubmed/16189079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4046-4051.2005
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