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In Vitro Development of Resistance to Human Immunodeficiency Virus Protease Inhibitor GW640385
Development of in vitro resistance to GW640385, a new human immunodeficiency virus type 1 protease inhibitor, was studied. Variants characterized included one with <4-fold resistance and amino acid substitutions Q58E/A71V (protease) and P452K (Gag) and one with >50-fold resistance and amino ac...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1426426/ https://ncbi.nlm.nih.gov/pubmed/16495277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.1092-1095.2006 |
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