Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity

Maraviroc (UK-427,857) is a selective CCR5 antagonist with potent anti-human immunodeficiency virus type 1 (HIV-1) activity and favorable pharmacological properties. Maraviroc is the product of a medicinal chemistry effort initiated following identification of an imidazopyridine CCR5 ligand from a h...

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מידע ביבליוגרפי
Main Authors: Dorr, Patrick, Westby, Mike, Dobbs, Susan, Griffin, Paul, Irvine, Becky, Macartney, Malcolm, Mori, Julie, Rickett, Graham, Smith-Burchnell, Caroline, Napier, Carolyn, Webster, Rob, Armour, Duncan, Price, David, Stammen, Blanda, Wood, Anthony, Perros, Manos
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280117/
https://ncbi.nlm.nih.gov/pubmed/16251317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4721-4732.2005
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