Emergence of CXCR4-Using Human Immunodeficiency Virus Type 1 (HIV-1) Variants in a Minority of HIV-1-Infected Patients following Treatment with the CCR5 Antagonist Maraviroc Is from a Pretreatment CXCR4-Using Virus Reservoir

Antagonists of the human immunodeficiency virus type 1 (HIV-1) coreceptor, CCR5, are being developed as the first anti-HIV agents acting on a host cell target. We monitored the coreceptor tropism of circulating virus, screened at baseline for coreceptor tropism, in 64 HIV-1-infected patients who rec...

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Détails bibliographiques
Auteurs principaux: Westby, Mike, Lewis, Marilyn, Whitcomb, Jeannette, Youle, Mike, Pozniak, Anton L., James, Ian T., Jenkins, Tim M., Perros, Manos, van der Ryst, Elna
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472081/
https://ncbi.nlm.nih.gov/pubmed/16641282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4909-4920.2006
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