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Efficacy of Ravuconazole in Treatment of Systemic Murine Histoplasmosis

Ravuconazole (RCZ) was evaluated for efficacy in comparison to fluconazole (FCZ) and itraconazole (ITZ) in murine models of disseminated histoplasmosis. All regimens tested prolonged survival (P < 0.05 to 0.0001). At equivalent doses of 50 mg/kg of body weight, RCZ and ITZ were equally effective and...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Clemons, K. V., Martinez, M., Calderon, L., Stevens, D. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.922-924.2002
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