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Efficacy of Ravuconazole in Treatment of Systemic Murine Histoplasmosis

Ravuconazole (RCZ) was evaluated for efficacy in comparison to fluconazole (FCZ) and itraconazole (ITZ) in murine models of disseminated histoplasmosis. All regimens tested prolonged survival (P < 0.05 to 0.0001). At equivalent doses of 50 mg/kg of body weight, RCZ and ITZ were equally effective and...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Clemons, K. V., Martinez, M., Calderon, L., Stevens, D. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.922-924.2002
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