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Efficacy of Ravuconazole in Treatment of Systemic Murine Histoplasmosis

Ravuconazole (RCZ) was evaluated for efficacy in comparison to fluconazole (FCZ) and itraconazole (ITZ) in murine models of disseminated histoplasmosis. All regimens tested prolonged survival (P < 0.05 to 0.0001). At equivalent doses of 50 mg/kg of body weight, RCZ and ITZ were equally effective and...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Clemons, K. V., Martinez, M., Calderon, L., Stevens, D. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.922-924.2002
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