Pharmacokinetic Modeling and Simulations of Interaction of Amprenavir and Ritonavir
Data from three pharmacokinetic drug interaction studies of amprenavir and ritonavir were used to develop a pharmacokinetic interaction model using NONMEM (nonlinear mixed-effect model). A two-compartment linear model with first-order absorption best fit the amprenavir data, while a one-compartment...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.746-754.2002 |
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