Pharmacokinetic Modeling and Simulations of Interaction of Amprenavir and Ritonavir

Data from three pharmacokinetic drug interaction studies of amprenavir and ritonavir were used to develop a pharmacokinetic interaction model using NONMEM (nonlinear mixed-effect model). A two-compartment linear model with first-order absorption best fit the amprenavir data, while a one-compartment...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Sale, Mark, Sadler, Brian M., Stein, Daniel S.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2002
Aiheet:	Pharmacology
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.746-754.2002
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