The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes

We identified the genes encoding the AcrA-AcrB-TolC efflux pump in Enterobacter aerogenes and constructed acrAB and tolC mutants from a multidrug-resistant isolate. Both derivatives were more susceptible to antibiotics than the parental strain. Sequence analysis and complementation experiments revea...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Pradel, Elizabeth, Pagès, Jean-Marie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2640-2643.2002
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