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Mapping the Role of AcrAB-TolC Efflux Pumps in the Evolution of Antibiotic Resistance Reveals Near-MIC Treatments Facilitate Resistance Acquisition

ABSTRACT Antibiotic resistance has become a major public health concern as bacteria evolve to evade drugs, leading to recurring infections and a decrease in antibiotic efficacy. Systematic efforts have revealed mechanisms involved in resistance. Yet, in many cases, how these specific mechanisms acce...

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Principais autores: Ariel M. Langevin, Imane El Meouche, Mary J. Dunlop
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020-12-01
coleção:mSphere
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Acesso em linha:https://journals.asm.org/doi/10.1128/mSphere.01056-20
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