Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system
Tripartite multidrug efflux pumps that span the cell envelope are essential for antibiotic resistance in Gram-negative bacteria. Here, we report cryo-EM structures of two endogenous efflux complexes from Escherichia coli: a TolC–YbjP subcomplex at 3.56 Å resolution and the complete TolC–YbjP–AcrABZ...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
eLife Sciences Publications Ltd
2026-04-01
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| श्रृंखला: | eLife |
| विषय: | |
| ऑनलाइन पहुंच: | https://elifesciences.org/articles/109684 |
| टैग: |
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