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The AcrAB-TolC Efflux Pump Contributes to Multidrug Resistance in the Nosocomial Pathogen Enterobacter aerogenes

We identified the genes encoding the AcrA-AcrB-TolC efflux pump in Enterobacter aerogenes and constructed acrAB and tolC mutants from a multidrug-resistant isolate. Both derivatives were more susceptible to antibiotics than the parental strain. Sequence analysis and complementation experiments revea...

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Detalhes bibliográficos
Main Authors: Pradel, Elizabeth, Pagès, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127391/
https://ncbi.nlm.nih.gov/pubmed/12121946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2640-2643.2002
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