Simple Fibroblast-Based Assay for Screening of New Antimicrobial Drugs against Mycobacterium tuberculosis

In this study, we propose a simple and reproducible host-cell-based assay for the screening of antimycobacterial drugs that is suitable for drug discovery. The method evaluates both antimycobacterial activity of the drugs and their cytotoxicity to host cells. The basis of this simple fibroblast-base...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Takii, Takemasa, Yamamoto, Yoshifumi, Chiba, Taku, Abe, Chiyoji, Belisle, John T., Brennan, Patrick J., Onozaki, Kikuo
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Susceptibility
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2533-2539.2002
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