Simple Fibroblast-Based Assay for Screening of New Antimicrobial Drugs against Mycobacterium tuberculosis

In this study, we propose a simple and reproducible host-cell-based assay for the screening of antimycobacterial drugs that is suitable for drug discovery. The method evaluates both antimycobacterial activity of the drugs and their cytotoxicity to host cells. The basis of this simple fibroblast-base...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Takii, Takemasa, Yamamoto, Yoshifumi, Chiba, Taku, Abe, Chiyoji, Belisle, John T., Brennan, Patrick J., Onozaki, Kikuo
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Susceptibility
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2533-2539.2002
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