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Simple Fibroblast-Based Assay for Screening of New Antimicrobial Drugs against Mycobacterium tuberculosis

In this study, we propose a simple and reproducible host-cell-based assay for the screening of antimycobacterial drugs that is suitable for drug discovery. The method evaluates both antimycobacterial activity of the drugs and their cytotoxicity to host cells. The basis of this simple fibroblast-base...

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Dettagli Bibliografici
Autori principali: Takii, Takemasa, Yamamoto, Yoshifumi, Chiba, Taku, Abe, Chiyoji, Belisle, John T., Brennan, Patrick J., Onozaki, Kikuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127360/
https://ncbi.nlm.nih.gov/pubmed/12121929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2533-2539.2002
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