Simple Fibroblast-Based Assay for Screening of New Antimicrobial Drugs against Mycobacterium tuberculosis

In this study, we propose a simple and reproducible host-cell-based assay for the screening of antimycobacterial drugs that is suitable for drug discovery. The method evaluates both antimycobacterial activity of the drugs and their cytotoxicity to host cells. The basis of this simple fibroblast-base...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Takii, Takemasa, Yamamoto, Yoshifumi, Chiba, Taku, Abe, Chiyoji, Belisle, John T., Brennan, Patrick J., Onozaki, Kikuo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Susceptibility
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2533-2539.2002
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