Simple Fibroblast-Based Assay for Screening of New Antimicrobial Drugs against Mycobacterium tuberculosis

In this study, we propose a simple and reproducible host-cell-based assay for the screening of antimycobacterial drugs that is suitable for drug discovery. The method evaluates both antimycobacterial activity of the drugs and their cytotoxicity to host cells. The basis of this simple fibroblast-base...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Takii, Takemasa, Yamamoto, Yoshifumi, Chiba, Taku, Abe, Chiyoji, Belisle, John T., Brennan, Patrick J., Onozaki, Kikuo
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Susceptibility
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2533-2539.2002
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