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Small-Colony Mutants of Staphylococcus aureus Allow Selection of Gyrase-Mediated Resistance to Dual-Target Fluoroquinolones

Fluoroquinolones acting equally through DNA gyrase and topoisomerase IV in vivo are considered desirable in requiring two target mutations for emergence of resistant bacteria. To investigate this idea, we have studied the response of Staphylococcus aureus RN4220 to stepwise challenge with sparfloxac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Pan, Xiao-Su, Hamlyn, Penelope J., Talens-Visconti, Raquel, Alovero, Fabiana L., Manzo, Ruben H., Fisher, L. Mark
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC127329/
https://ncbi.nlm.nih.gov/pubmed/12121924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2498-2506.2002
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