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Genetic Divergence of Human Immunodeficiency Virus Type 1 Ethiopian Clade C Reverse Transcriptase (RT) and Rapid Development of Resistance against Nonnucleoside Inhibitors of RT

We sequenced and phylogenetically analyzed the reverse transcriptase (RT) region of five human immunodeficiency virus type 1 isolates from treatment-naive Ethiopian émigrés to Israel. Heteroduplex mobility assays were performed to confirm the clade C status of env genomic regions. The RT sequences s...

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Published in:Antimicrob Agents Chemother
Main Authors: Loemba, Hugues, Brenner, Bluma, Parniak, Michael A., Ma'ayan, Shlomo, Spira, Bonnie, Moisi, Daniela, Oliveira, Maureen, Detorio, Mervi, Wainberg, Mark A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2087-2094.2002
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