Antitrypanosomal Activities of Proteasome Inhibitors
Seven peptidyl proteasome inhibitors were tested for in vitro activity against Trypanosoma brucei bloodstream forms. Two compounds showed activity in the low nanomolar range. In general, trypanosomes were more susceptible to the compounds than were human HL-60 cells. The data support the potential o...
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| Publié dans: | Antimicrob Agents Chemother |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.2038-2040.2002 |
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