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Antitrypanosomal Activities of Proteasome Inhibitors

Seven peptidyl proteasome inhibitors were tested for in vitro activity against Trypanosoma brucei bloodstream forms. Two compounds showed activity in the low nanomolar range. In general, trypanosomes were more susceptible to the compounds than were human HL-60 cells. The data support the potential o...

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Detaylı Bibliyografya
Asıl Yazarlar: Nkemgu-Njinkeng, Joseph, Rosenkranz, Vera, Wink, Michael, Steverding, Dietmar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC127253/
https://ncbi.nlm.nih.gov/pubmed/12019136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.2038-2040.2002
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