Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

This work describes the discovery and characterization of a novel series of tricyclic natural product-derived metallo-β-lactamase inhibitors. Natural product screening of the Bacillus cereus II enzyme identified an extract from a strain of Chaetomium funicola with inhibitory activity against metallo...

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Foilsithe in:	Antimicrob Agents Chemother
Príomhchruthaitheoirí:	Payne, David J., Hueso-Rodríguez, Juan Antonio, Boyd, Helen, Concha, Néstor O., Janson, Cheryl A., Gilpin, Martin, Bateson, John H., Cheever, Christy, Niconovich, Nancy L., Pearson, Stewart, Rittenhouse, Stephen, Tew, David, Díez, Emilio, Pérez, Paloma, de la Fuente, Jesus, Rees, Michael, Rivera-Sagredo, Alfonso
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	American Society for Microbiology (ASM) 2002
Ábhair:	Chemistry; Biosynthesis
Rochtain ar líne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1880-1886.2002
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