Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

This work describes the discovery and characterization of a novel series of tricyclic natural product-derived metallo-β-lactamase inhibitors. Natural product screening of the Bacillus cereus II enzyme identified an extract from a strain of Chaetomium funicola with inhibitory activity against metallo...

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出版年:	Antimicrob Agents Chemother
主要な著者:	Payne, David J., Hueso-Rodríguez, Juan Antonio, Boyd, Helen, Concha, Néstor O., Janson, Cheryl A., Gilpin, Martin, Bateson, John H., Cheever, Christy, Niconovich, Nancy L., Pearson, Stewart, Rittenhouse, Stephen, Tew, David, Díez, Emilio, Pérez, Paloma, de la Fuente, Jesus, Rees, Michael, Rivera-Sagredo, Alfonso
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Chemistry; Biosynthesis
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1880-1886.2002
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