Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

This work describes the discovery and characterization of a novel series of tricyclic natural product-derived metallo-β-lactamase inhibitors. Natural product screening of the Bacillus cereus II enzyme identified an extract from a strain of Chaetomium funicola with inhibitory activity against metallo...

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מידע ביבליוגרפי

הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Payne, David J., Hueso-Rodríguez, Juan Antonio, Boyd, Helen, Concha, Néstor O., Janson, Cheryl A., Gilpin, Martin, Bateson, John H., Cheever, Christy, Niconovich, Nancy L., Pearson, Stewart, Rittenhouse, Stephen, Tew, David, Díez, Emilio, Pérez, Paloma, de la Fuente, Jesus, Rees, Michael, Rivera-Sagredo, Alfonso
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2002
נושאים:	Chemistry; Biosynthesis
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1880-1886.2002
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