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Single-Dose Pharmacokinetics of Amprenavir Coadministered with Grapefruit Juice
In this crossover study in 12 healthy volunteers, coadministration of amprenavir (1,200 mg; single dose) with grapefruit juice slightly reduced the maximum concentration of drug in serum (C(max)) compared to administration with water (7.11 versus 9.10 μg/ml), slightly increased the time to C(max) (1...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127190/ https://ncbi.nlm.nih.gov/pubmed/11959608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1589-1590.2002 |
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