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Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells

Transforming growth factor-β (TGF-β), one of the most abundant cytokines in bone matrix, has positive and negative effects on bone formation, although the molecular mechanisms of these effects are not fully understood. Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, induce bone...

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Autors principals: Maeda, Shingo, Hayashi, Makoto, Komiya, Setsuro, Imamura, Takeshi, Miyazono, Kohei
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271802/
https://ncbi.nlm.nih.gov/pubmed/14749725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600067
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