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Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells

Transforming growth factor-β (TGF-β), one of the most abundant cytokines in bone matrix, has positive and negative effects on bone formation, although the molecular mechanisms of these effects are not fully understood. Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, induce bone...

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Bibliographic Details
Main Authors: Maeda, Shingo, Hayashi, Makoto, Komiya, Setsuro, Imamura, Takeshi, Miyazono, Kohei
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271802/
https://ncbi.nlm.nih.gov/pubmed/14749725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600067
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