SnoN Suppresses Maturation of Chondrocytes by Mediating Signal Cross-talk between Transforming Growth Factor-β and Bone Morphogenetic Protein Pathways

Hypertrophic maturation of chondrocytes is a crucial step in endochondral ossification, whereas abnormally accelerated differentiation of hypertrophic chondrocytes in articular cartilage is linked to pathogenesis of osteoarthritis. This cellular process is promoted or inhibited by bone morphogenetic...

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Detalhes bibliográficos
Main Authors: Kawamura, Ichiro, Maeda, Shingo, Imamura, Katsuyuki, Setoguchi, Takao, Yokouchi, Masahiro, Ishidou, Yasuhiro, Komiya, Setsuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436559/
https://ncbi.nlm.nih.gov/pubmed/22767605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349415
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