SnoN Suppresses Maturation of Chondrocytes by Mediating Signal Cross-talk between Transforming Growth Factor-β and Bone Morphogenetic Protein Pathways

Hypertrophic maturation of chondrocytes is a crucial step in endochondral ossification, whereas abnormally accelerated differentiation of hypertrophic chondrocytes in articular cartilage is linked to pathogenesis of osteoarthritis. This cellular process is promoted or inhibited by bone morphogenetic...

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Bibliografski detalji
Glavni autori: Kawamura, Ichiro, Maeda, Shingo, Imamura, Katsuyuki, Setoguchi, Takao, Yokouchi, Masahiro, Ishidou, Yasuhiro, Komiya, Setsuro
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Signal Transduction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436559/
https://ncbi.nlm.nih.gov/pubmed/22767605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349415
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