Lack of Interaction of Fluoroquinolones with Lipopolysaccharides

Fluoroquinolones are known to chelate with di- and trivalent cations, and it has accordingly been claimed that they perturb the integrity of the outer membrane (OM) of gram-negative bacteria. So far, chelation has not been assessed in biologically relevant test systems. Therefore, we investigated th...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lindner, B., Wiese, A., Brandenburg, K., Seydel, U., Dalhoff, A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Mechanisms of Action: Physiological Effects
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1568-1570.2002
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