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Antitrypanosomal Activities of Tryptanthrins

New drugs and molecular targets are needed against Trypanosoma brucei, the protozoan that causes African sleeping sickness. Tryptanthrin (indolo[2,1-b]quinazoline-6,12-dione), a traditional antifungal agent, and 11 analogs were tested against T. brucei in vitro. The greatest activity was conferred b...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Scovill, John, Blank, Elizabeth, Konnick, Michael, Nenortas, Elizabeth, Shapiro, Theresa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.882-883.2002
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