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Lack of Interaction of Fluoroquinolones with Lipopolysaccharides

Fluoroquinolones are known to chelate with di- and trivalent cations, and it has accordingly been claimed that they perturb the integrity of the outer membrane (OM) of gram-negative bacteria. So far, chelation has not been assessed in biologically relevant test systems. Therefore, we investigated th...

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Autors principals: Lindner, B., Wiese, A., Brandenburg, K., Seydel, U., Dalhoff, A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127130/
https://ncbi.nlm.nih.gov/pubmed/11959601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1568-1570.2002
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