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Alternative splicing and nonsense-mediated mRNA decay regulate mammalian ribosomal gene expression
Messenger RNAs containing premature stop codons are generally targeted for degradation through nonsense-mediated mRNA decay (NMD). This mechanism degrades aberrant transcripts derived from mutant genes containing nonsense or frameshift mutations. Wild-type genes also give rise to transcripts targete...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1270949/ https://ncbi.nlm.nih.gov/pubmed/16254077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki905 |
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