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Live Imaging of Drosophila Brain Neuroblasts Reveals a Role for Lis1/Dynactin in Spindle Assembly and Mitotic Checkpoint Control

Lis1 is required for nuclear migration in fungi, cell cycle progression in mammals, and the formation of a folded cerebral cortex in humans. Lis1 binds dynactin and the dynein motor complex, but the role of Lis1 in many dynein/dynactin-dependent processes is not clearly understood. Here we generate...

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Detalhes bibliográficos
Main Authors: Siller, Karsten H., Serr, Madeline, Steward, Ruth, Hays, Tom S., Doe, Chris Q.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266413/
https://ncbi.nlm.nih.gov/pubmed/16107559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-04-0338
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