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Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
DNA hypomethylation on pericentromeric satellite regions is an early and frequent event associated with heterochromatin instability during human hepatocarcinogenesis. A DNA methyltransferase, DNMT3b, is required for methylation on pericentromeric satellite regions during mouse development. To clarif...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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The National Academy of Sciences
2002
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126624/ https://ncbi.nlm.nih.gov/pubmed/12110732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152121799 |
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