Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis

DNA hypomethylation on pericentromeric satellite regions is an early and frequent event associated with heterochromatin instability during human hepatocarcinogenesis. A DNA methyltransferase, DNMT3b, is required for methylation on pericentromeric satellite regions during mouse development. To clarif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Saito, Yoshimasa, Kanai, Yae, Sakamoto, Michiie, Saito, Hidetsugu, Ishii, Hiromasa, Hirohashi, Setsuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2002
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC126624/
https://ncbi.nlm.nih.gov/pubmed/12110732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152121799
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