Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis

DNA hypomethylation on pericentromeric satellite regions is an early and frequent event associated with heterochromatin instability during human hepatocarcinogenesis. A DNA methyltransferase, DNMT3b, is required for methylation on pericentromeric satellite regions during mouse development. To clarif...

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Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Saito, Yoshimasa, Kanai, Yae, Sakamoto, Michiie, Saito, Hidetsugu, Ishii, Hiromasa, Hirohashi, Setsuo
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 2002
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12110732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152121799
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