Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis

DNA hypomethylation on pericentromeric satellite regions is an early and frequent event associated with heterochromatin instability during human hepatocarcinogenesis. A DNA methyltransferase, DNMT3b, is required for methylation on pericentromeric satellite regions during mouse development. To clarif...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Saito, Yoshimasa, Kanai, Yae, Sakamoto, Michiie, Saito, Hidetsugu, Ishii, Hiromasa, Hirohashi, Setsuo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12110732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152121799
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!