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Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis

In order to clarify the significance of DNA methylation in both earlier and later stages of hepatocarcinogenesis, the DNA methylation state on chromosome 16, on which loss of heterozygosity (LOH) has frequently been detected in human hepatocellular carcinomas (HCCs), was examined. DNA from primary H...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kanai, Yae, Ushijima, Saori, Tsuda, Hitoshi, Sakamoto, Michiie, Sugimura, Takashi, Hirohashi, Setsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921026/
https://ncbi.nlm.nih.gov/pubmed/9045955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb03135.x
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