Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis

In order to clarify the significance of DNA methylation in both earlier and later stages of hepatocarcinogenesis, the DNA methylation state on chromosome 16, on which loss of heterozygosity (LOH) has frequently been detected in human hepatocellular carcinomas (HCCs), was examined. DNA from primary H...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Kanai, Yae, Ushijima, Saori, Tsuda, Hitoshi, Sakamoto, Michiie, Sugimura, Takashi, Hirohashi, Setsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1996
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921026/
https://ncbi.nlm.nih.gov/pubmed/9045955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1996.tb03135.x
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