Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: Implications for tauopathies

Frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) is caused by mutations in the gene encoding the microtubule-associated protein, tau. Some FTDP-17 mutations affect exon 10 splicing. To correct aberrant exon 10 splicing while retaining endogenous transcriptional control, we...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rodriguez-Martin, Teresa, Garcia-Blanco, Mariano A., Mansfield, S. Gary, Grover, Andrew C., Hutton, Michael, Yu, Qingming, Zhou, Jianhua, Anderton, Brian H., Gallo, Jean-Marc
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266082/
https://ncbi.nlm.nih.gov/pubmed/16230627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503150102
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