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Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing
In the human genome, the majority of protein-encoding genes are interrupted by introns, which are removed from primary transcripts by a macromolecular enzyme known as the spliceosome. Spliceosomes can constitutively remove all the introns in a primary transcript to yield a fully spliced mRNA or alte...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171395/ https://ncbi.nlm.nih.gov/pubmed/12925685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319462 |
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