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Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing

In the human genome, the majority of protein-encoding genes are interrupted by introns, which are removed from primary transcripts by a macromolecular enzyme known as the spliceosome. Spliceosomes can constitutively remove all the introns in a primary transcript to yield a fully spliced mRNA or alte...

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Bibliografiske detaljer
Hovedforfatter: Garcia-Blanco, Mariano A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC171395/
https://ncbi.nlm.nih.gov/pubmed/12925685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319462
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