Loss of Bif-1 Suppresses Bax/Bak Conformational Change and Mitochondrial Apoptosis

Bif-1, a member of the endophilin B protein family, interacts with Bax and promotes interleukin-3 withdrawal-induced Bax conformational change and apoptosis when overexpressed in FL5.12 cells. Here, we provide evidence that Bif-1 plays a regulatory role in apoptotic activation of not only Bax but al...

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Bibliographische Detailangaben
Hauptverfasser: Takahashi, Yoshinori, Karbowski, Mariusz, Yamaguchi, Hirohito, Kazi, Aslamuzzaman, Wu, Jie, Sebti, Saïd M., Youle, Richard J., Wang, Hong-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265816/
https://ncbi.nlm.nih.gov/pubmed/16227588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9369-9382.2005
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