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Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis

Bax is a member of the Bcl-2 family of proteins known to regulate mitochondria-dependent programmed cell death. Early in apoptosis, Bax translocates from the cytosol to the mitochondrial membrane. We have identified by confocal and electron microscopy a novel step in the Bax proapoptotic mechanism i...

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Main Authors: Nechushtan, Amotz, Smith, Carolyn L., Lamensdorf, Itschak, Yoon, Soo-Han, Youle, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192024/
https://ncbi.nlm.nih.gov/pubmed/11402069
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