Loading...
Phosphorylation of BLM, Dissociation from Topoisomerase IIIα, and Colocalization with γ-H2AX after Topoisomerase I-Induced Replication Damage
Topoisomerase I-associated DNA single-strand breaks selectively trapped by camptothecins are lethal after being converted to double-strand breaks by replication fork collisions. BLM (Bloom's syndrome protein), a RecQ DNA helicase, and topoisomerase IIIα (Top3α) appear essential for the resoluti...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2005
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1265790/ https://ncbi.nlm.nih.gov/pubmed/16199871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.8925-8937.2005 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|