The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion

The Runx2 (Cbfa1/AML3) transcription factor and matrix metalloproteinase 9 (MMP9) are key regulators of growth plate maturation and bone formation. The genes for both proteins are characteristic markers of breast and prostate cancer cells that metastasize to bone. Here we experimentally addressed th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pratap, Jitesh, Javed, Amjad, Languino, Lucia R., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265732/
https://ncbi.nlm.nih.gov/pubmed/16166639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8581-8591.2005
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